Spravato
FDA-Approved For Treatment Resistant Depression
Some Patients Notice a Difference within Hours
Most Major Insurers Accepted, Including Medicare
REMS Certified, In-Clinic Safety Monitoring
Here's How Spravato Works
Spravato (esketamine) is FDA-approved for treatment-resistant depression, administered as a nasal spray under direct physician supervision, with required post-dose monitoring. It's delivered as part of a coordinated plan alongside your existing antidepressant, with a safety screen and REMS enrollment completed before your first dose.
01
The Right Candidate
Confirmed treatment-resistant depression and a careful medical/psychiatric eligibility screen.
02
The Right Protocol
REMS-supervised in-clinic dosing with BP checks and post-dose monitoring.
03
The Right Dosing
Monitored induction/maintenance nasal dosing with clinician checks for side effects.
04
The Right Setting & Team
Private rooms, trained staff, and direct psychiatrist oversight.
05
The Right Follow-Up
Aftercare/transport rules, coordinated meds/therapy, and maintenance planning.
Spravato Options
Spravato is REMS-supervised, in-clinic esketamine for treatment-resistant depression - physician-led with screening, monitored dosing, and follow-up.
- REMS in-clinic dosing - monitored nasal dosing with BP checks and post-dose observation.
- Candidate screening - confirm treatment-resistant depression.
- Dosing & monitoring - induction vs maintenance schedules with clinician checks.
- Coverage & cost - we handle prior authorizations and provide written estimates or packages.
Us vs Them
Why Patients Choose Evolve
Evolve
60–90 min psychiatric evaluation
Spravato administered on-site, every session
REMS-certified with safety monitoring included
Written treatment plan and scheduled follow-ups
Spravato, TMS, and medication coordinated in one place
Other Clinics
Rushed 10–15 min med checks
No in-house Spravato administration
No REMS certification or safety oversight
No structured follow-up plan
No coordination between your treatments or providers
Cost & Insurance
We accept most major insurers and help with benefits checks and prior authorizations for Spravato.
- In-network: Spravato often requires prior authorization and REMS enrollment - we verify your benefits and estimate your patient cost.
- Out-of-network: Superbill available for reimbursement.
- REMS & in-clinic care: Spravato is administered in clinic under REMS supervision; this can affect coverage and cost.
- Self-pay & packages: Transparent package pricing and written estimates before care.
What to Expect at Your First Visit
What Patients Want to Know
What am I going to get?
A psychiatric evaluation, a REMS-supervised Spravato treatment plan, in-clinic sessions with safety monitoring, and coordinated follow-up care.
How much will it cost?
Cost depends on your insurance and how many sessions are needed. We verify your benefits, handle prior authorization, and give you a written estimate before you start.
How little of my time will it take?
Your first visit is 60–90 minutes. Each Spravato session requires at least two hours in clinic — this is a REMS requirement, not something we can shorten.
How little hassle will it be?
We handle REMS enrollment, insurance verification, and prior authorization. You show up — we manage the process.
How little risk is involved?
Spravato is FDA-approved. Side effects like dissociation or dizziness are possible, which is why every session is monitored in clinic. You cannot drive after a session.
What if I have other questions?
Call or message us before booking. We're happy to walk you through whether Spravato is the right fit before you commit to anything.
Who is this clinic?
Evolve Brain Health is a psychiatric practice in Stamford, CT led by Dr. Thomas Knightly, MD. We offer TMS, Spravato, medication management, and therapy under one roof.
Can I trust this clinic?
We're a REMS-certified Spravato provider. Dr. Knightly oversees every treatment plan personally. Check our Google reviews - patients speak for themselves.
Patient Reviews
Become a Patient
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