Fairfield County's Interventional
Psychiatry Specialists
Tried 2+ antidepressants? There's another way.
Spravato® (esketamine) is FDA-approved for treatment-resistant depression, taken in our office with our team beside you. Covered by most major insurance, including Medicare and Medicaid. Led by Stanford-trained psychiatrist Dr. Thomas Knightly in Stamford, CT.
Covered by most major insurance · Appointments available this week · No referral needed
Covered by most major
US health insurers.







Don't see your plan listed? Give us a call and we'll confirm your coverage.
Many patients pay between $0 and $25 per session, depending on the plan. We verify your exact cost for free and handle prior authorization.
5.0 Google Rating
Stanford-Trained Leadership
FDA-Backed Treatments
No Referral Needed
Relief that
doesn't take months.
Days
many patients notice a change within days, not weeks
2X
sessions per week during the first month, then tapering down
Taken together with your oral antidepressant, under our team's supervision.
BASED ON PUBLISHED CLINICAL DATA FOR SPRAVATO
When pills alone aren't enough.
You've given the antidepressants a real shot. Two, three, maybe more. Spravato works differently: it targets a different brain pathway, which is why it can work when other medications haven't.
Every session happens in our office. You self-administer the nasal spray under supervision, then relax in a private room while our team monitors you for two hours. You'll need a ride home.
Your session, hour by hour.
Every Spravato session happens in our office. Here is exactly how one goes.

A quiet room, a screen, and a trained specialist with you.
Two things to plan
Arrange a ride home. No food for 2 hours beforehand.
Vitals and settling in
We take your blood pressure and settle you into a private room.
You self-administer
You use the nasal spray yourself, with our team beside you.
Rest and monitoring
You relax while we monitor you. Vitals are checked again before you leave.
Clearance and ride
We confirm you are stable. Your ride takes you home. No driving until the next day.
A clear schedule, from day one.
Spravato follows a defined course. You'll always know what's next.
Twice a week
- Eight sessions over four weeks
- Each visit is about two hours, monitored
Once a week
- Weekly sessions as your response builds
- Progress tracked at every visit
Every 1 to 2 weeks
- Spacing based on how you respond
- Your provider adjusts the plan with you
I struggled with severe depression for years and tried many medications with little success. I did the research and found Evolve Brain Health. I completed accelerated TMS and I feel better. I never thought I'd say that. You will not find a more kind and empathetic staff.
★★★★★ Lawrence B. · Google review
Founded by a Stanford Brain Stimulation Lab
psychiatrist.
Dr. Thomas Knightly
Founder & Medical Director · Evolve Brain Health
Evolve was founded by Dr. Thomas Knightly: Stanford graduate, clinical assistant professor at Stanford, and member of the Stanford Brain Stimulation Lab, the research group behind the accelerated TMS protocols now transforming depression care. Every treatment plan at Evolve is physician-designed and personally overseen.
Your care is delivered by clinicians personally trained and supervised by Dr. Knightly, following the standards and protocols he sets for every patient at Evolve.

Julianne Vesciglio
PMHNP

Renee Fontaine
PMHNP
A calm place
to get better.
No hospital feel. Private treatment rooms, comfortable chairs, and a team that knows you by name.

Waiting Area

Spravato Treatment Room

Reception
From people who've been here.
Frequently Asked Questions
Does insurance cover Spravato in Connecticut?
Yes. Spravato is covered by most major plans, including Aetna, Cigna, Anthem, UnitedHealthcare, ConnectiCare, Husky, and Medicare, for treatment-resistant depression. We verify your benefits, handle prior authorization, and enroll you in the manufacturer savings program.
How much will I pay out of pocket?
For most covered patients, out-of-pocket cost is comparable to a standard specialist copay, typically between $0 and $25 per session depending on your plan. We confirm your exact cost before you start. No surprise bills.
What does a session feel like?
Most people feel relaxed or a bit floaty for about an hour. You rest in a private room while we monitor you. The effects wear off before you leave.
Can I drive home after?
No. You'll need a ride home after each session, and no driving until the next day after a full night's sleep.
Do I keep taking my antidepressant?
Usually yes. Spravato is taken together with an oral antidepressant. Your provider will review your medications at your evaluation.
How fast does it work?
Many patients notice improvement within days. Your provider tracks your response at every session and adjusts the plan with you.
Is Spravato safe?
Spravato is FDA-approved and administered under direct medical supervision with two-hour monitoring per FDA REMS requirements at every session.
Do I need a referral?
No referral is needed. Book a free consultation directly.
You've tried waiting it out.
Try something different.
Free 10-minute consultation. No pressure, no obligation.
No obligation. Same-day call or text back.
Your consult is a relaxed 10-minute call. No pressure, no questions you aren't ready for, and no commitment.
Prefer to schedule a call? Pick a time now or call or text (203) 439-5050













